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Fetomaternal Bleed, Flow Cytometry

Test Code


CPT Code(s)


Preferred Specimen(s)

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

0.5 mL

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 4 days
Frozen: Unacceptable

Reject Criteria

Received frozen


Flow Cytometry (FC)

Reference Range(s)

Fetomaternal Bleed <0.1% Fetal Cells

Clinical Significance

This test quantifies the volume of fetal-maternal hemorrhage (FMH). In Rh-positive mothers it is used solely to establish the volume of fetal hemorrhage into the maternal circulation. In Rh negative mothers it is also used to determine if an increased dose of Rh immune globulin (RhIG, anti-D antibody) is necessary.
Based on an assumed total maternal circulatory volume of 5,000 mL, the FMH is calculated by multiplying the %Fetal Cells by 50. Please refer to the most current AABB Technical Manual for RhIG dosage information.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
FMBFetomaternal Bleed,FCPending assignment

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.