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Osteocalcin, N-MID

Test Code

16322

CPT Code(s)

83937

Preferred Specimen(s)

1 mL serum (R, red-top tube, no addtive)

Minimum Volume

0.5 mL

Alternative Specimen(s)

1 mL serum (SS, serum separator tube)

Collection Instructions

Allow blood to clot at room temperature (20-26° C) and centrifuge immediately to separate the serum from the cells. Freeze as soon as possible.

Specimen Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable

Refrigerated: 24 hours

Frozen 21 days

Methodology

Electrochemiluminescence (ECLIA)

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

Setup Schedule

Mon., Wed., Fri., a.m.; Report available: 3 Days

Reference Range(s)

Pediatrics: 5-9 years: 47-142 ng/mL
  10-13 years: 49-167 ng/mL
14-17 years: Males: 26-203 ng/mL
  Females: 14-85 ng/mL
Adults: Males: 9-38 ng/mL
  Females: 8-32 ng/mL

Clinical Significance

Osteocalcin, the most abundant non-collagen protein in bone matrix, is a bone-specific, calcium binding protein. Serum osteocalcin levels are related to the rate of bone turnover in various disorders of bone metabolism, eg, osteoporosis, primary and secondary hyperparathyroidism, and Paget's disease.

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

(The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.)

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.