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To view specimen requirements and codes please select your laboratory:
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0.5 mL serum
For red-top tubes, allow blood to clot 10-15 minutes at room temperature. Separate serum from cells and refrigerate. If sample collected in glass collection tube, transfer to plastic container.
Plastic screw-cap vial
Refrigerated (cold packs)
Room temperature: 48 hours
Refrigerated: 5 days
Frozen -20° C: 28 days
Frozen -70° C: 21 days
Glass tubes (red-top or SST®) • Received room temperature
Liquid Chromatography/Mass Spectrometry (LC/MS)
This test was developed and its performance characteristics were determined by Quest Diagnostics Nichols Institute, San Juan Capistrano. Performance characteristics refer to the analytical performance of the test.
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
Set up: Mon-Fri, Sun p.m.; Report available: 5 days
See Laboratory Report
Insulin-like growth factor I (IGF-I, or somatomedin C), a protein involved in stimulating somatic growth, is regulated principally by growth hormone (GH) and nutritional intake. IGF-I is transported in serum by several proteins; this helps maintain relatively high IGF-I plasma levels and minimizes fluctuations in serum IGF-I concentrations.
Measuring IGF-I is useful in several growth-related disorders. Dwarfism caused by deficiency of growth hormone (hypopituitarism) results in decreased serum levels of IGF-I, while acromegaly (growth hormone excess) results in elevated levels of IGF-I. IGF-I measurements are also helpful in assessing nutritional status; levels are reduced in undernutrition and restored with a proper diet.
Somatomedin-C, Insulin-Like Growth Factor, IGF-1
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
(The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.)
* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.