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Mannose-Binding Lectin (MBL)

Test Code

16039

CPT Code(s)

83520

Patient Preparation

Overnight fasting is preferred

Preferred Specimen(s)

1 mL frozen serum

Minimum Volume

0.3 mL

Collection Instructions

Do not submit specimens that have been heat treated. Do not submit the sample in a glass tube.

Transport Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: 4 hours
Refrigerated: 4 hours
Frozen: 21 days

Reject Criteria

Hemolysis • Lipemia • Heat treated • Specimens containing visible particular matter • Received room temperature • Received refrigerated

Methodology

Enzyme Linked Immunosorbent Immunoassay (ELISA)

This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

Setup Schedule

Set up: Thurs; Report available: 8 days

Reference Range(s)

Mannan-Binding Lectin (MBL) is a serum collection (c-type lectin) and is considered an important component of the innate immune system. Clinical studies have used 50 or 100 ng/mL to define severe MBL deficiency. MBL is also known to activate the classical complement pathway through its binding to serine proteases MASP-2 and MASP-1. MBL deficiency has been associated with recurrent infections in children 6 months to 17 months of age, during the time when the adaptive immune system (IgG production) is not fully mature.

Clinical Significance

In conjunction with clinical findings and other laboratory tests, the deficiency of Mannose Binding Lectin (MBL) can be used to aid in the determination of susceptibility to infection.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result
Code
Result NameLOINC CodeComponent Name
86000348MANNOSE-BINDING LECTIN30152-3Mannose-binding protein

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.