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Mannose-Binding Lectin (MBL)
Overnight fasting is preferred
1 mL serum
Do not submit specimens that have been heat treated. Do not submit the sample in a glass tube.
Plastic screw-cap vial
Room temperature: 4 hours
Refrigerated: 4 hours
Frozen: 21 days
Hemolysis • Lipemia • Heat treated • Specimens containing visible particular matter
Enzyme Linked Immunosorbent Immunoassay (ELISA)
|Quest Diagnostics Nichols Institute-San Juan Capistrano, CA|
|33608 Ortega Highway|
|San Juan Capistrano, CA 92675-2042|
Set up: Thurs; Report available: 8 days
Mannan-Binding Lectin (MBL) is a serum collection (c-type lectin) and is considered an important component of the innate immune system. Clinical studies have used 50 or 100 ng/mL to define severe MBL deficiency. MBL is also known to activate the classical complement pathway through its binding to serine proteases MASP-2 and MASP-1. MBL deficiency has been associated with recurrent infections in children 6 months to 17 months of age, during the time when the adaptive immune system (IgG production) is not fully mature.
In conjunction with clinical findings and other laboratory tests, the deficiency of Mannose Binding Lectin (MBL) can be used to aid in the determination of susceptibility to infection.
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
(The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.)
* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.