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Calcium, 24-Hour Urine with Creatinine [1635X]

Test Code


CPT Code(s)

82340, 82570

Preferred Specimen(s)

10 mL aliquot of a well-mixed, 24-hour collection

See Urine in Blood, Urine and Stool section of Specimen Collection and Handling

Minimum Volume

2 mL

Alternative Specimen(s)

Urinalysis transport tube (yellow-top, blue fill line, preservative tube)

Collection Instructions

Collect urine with 25 mL of 6N HCl to maintain a pH below 3. It is acceptable to add preservative after collection if urine is refrigerated during collection. Adjust ph to <3.0. Record total volume and collection time on specimen container and requisition.
Refrigerate during and after collection. Do not include first morning specimen; collect all subsequent voidings. The last sample collected should be the first morning specimen voided the following morning at the same time as the previous morning's first voiding.

Specimen Container

Plastic screw-cap container

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 35 days
Frozen: 6 months

Reject Criteria



Spectrophotometry (SP)

Performing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Setup Schedule

Mon-Fri Morning, Evening, Night   Sat  Morning Sun Morning, Night; Report available: Next day


Oral contraceptive use may depress results. Requires accurate 24-hour urine collection.

Reference Range(s)

Unrestricted Calcium Diet

Male 55-300 mg/24 h
Female 35-250 mg/24 h
Restricted Calcium Diet
Male  55-200 mg/24 h 
Female 35-200 mg/24 h 

Calcium/Creatinine Ratio
Male 30-210 mg/g creat
Female 30-275 mg/g creat

Creatinine, 24-Hour Urine
<36 Months Not established
36 Months-8 Years 0.11-0.68 g/24 h
9-12 Years 0.17-1.41 g/24 h
13-17 Years 0.29-1.87 g/24 h
>17 Years 0.63-2.50 g/24 h

Clinical Significance

Abnormal levels are found in hyperparathyroidism, hyperthyroidism and Paget's Disease.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
0016Total Volume3167-4Specimen volume
14424ACreatinine, 24-Hour Urine2162-6Creatinine
15830ACalcium, 24-Hour Urine6874-2Calcium
15830BCalcium/Creatinine Ratio13717-4Calcium/Creatinine

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.