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Oligoclonal Bands, CSF [674X]
1 mL serum (R, red-top tube (no gel))
1 mL CSF submitted in a sterile, plastic, leak-proof container
Serum: 0.5 mL
CSF: 0.5 mL
1 mL Serum in (SS, serum separator tube)
1 mL CSF in a Sterile Container, leak-proof (Random)
It is preferred that the collection date and time be the same for both CSF and serum; however, it is acceptable for them to be drawn within 48 hours of each other. Client must be contacted when no serum is supplied to confirm the order. It is acceptable to send through CSF without serum when client has indicated to "run with serum control". CSF must be crystalline and clear. (CSF collection tube #4 preferred).
Plastic screw-cap vial
Refrigerated (cold packs)
Room temperature: 8 hours
Refrigerated: 5 days
Frozen: 14 days
|Quest Diagnostics Nichols Institute|
|14225 Newbrook Drive|
|Chantilly, VA 20153|
Mon.-Fri., p.m.; Report available: 4 Days
|The clinical significance of a numerical band count, determined by isoelectric focusing, has not been definitively defined. The data should be interpreted in conjunction with all pertinent clinical and laboratory data for this patient.|
Oligoclonal bands are present in the CSF of more than 85% of patients with clinically definite multiple sclerosis (MS). To distinguish between oligoclonal bands in the CSF due to a peripheral gammopathy and oligoclonal bands due to local production in the CNS, serum and CSF should be tested simultaneously. Oligoclonal bands can however, be observed in a variety of other diseases, e.g., subacute sclerosing panencephalitis, inflammatory polyneuropathy, CNS lupus, and brain tumors and infarctions.
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
(The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.)
* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.