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Oligoclonal Bands, CSF [674X]

Test Code

1418

CPT Code(s)

83916

Preferred Specimen(s)

1 mL CSF submitted in a sterile, plastic, leak-proof container and 1 mL serum

Minimum Volume

Serum: 0.5 mL
CSF: 0.5 mL

Collection Instructions

It is preferred that the collection date and time be the same for both CSF and serum; however, it is acceptable for them to be drawn within 48 hours of each other. Client must be contacted when no serum is supplied to confirm the order. It is acceptable to send through CSF without serum when client has indicated to "run with serum control". CSF must be crystalline and clear. (CSF collection tube #4 preferred).

Specimen Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 8 hours
Refrigerated: 5 days
Frozen: 14 days

Methodology

Isoelectric Focusing

Performing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Setup Schedule

Set up: Mon-Fri evenings; Report available: 4 days

Reference Range(s)

No bands
The clinical significance of a numerical band count, determined by isoelectric focusing, has not been definitively defined. The data should be interpreted in conjunction with all pertinent clinical and laboratory data for this patient.

Clinical Significance

Oligoclonal bands are present in the CSF of more than 85% of patients with clinically definite multiple sclerosis (MS). To distinguish between oligoclonal bands in the CSF due to a peripheral gammopathy and oligoclonal bands due to local production in the CNS, serum and CSF should be tested simultaneously. Oligoclonal bands can however, be observed in a variety of other diseases, e.g., subacute sclerosing panencephalitis, inflammatory polyneuropathy, CNS lupus, and brain tumors and infarctions.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result
Code
Result NameLOINC CodeComponent Name
1418AAOligoclonal Bands, CSF12782-9Protein fractions.oligoclonal bands

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.