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ANA Screen,IFA, with Reflex to Titer and Pattern/Lupus Panel 4

Test Code


CPT Code(s)

83516, 86038, 86160 (x2), 86225, 86235 (x5), 86376, 86431


ANA Screen, IFA with Reflex to Titer and Pattern; Complement Component C3c and C4c; DNA (ds) Antibody; Ribosomal P Antibody; Sm Antibody; Sm/RNP Antibody; Sjögren’s Antibodies (SS-A, SS-B); Thyroid Peroxidase Antibody (TPO); Scleroderma Antibody (Scl-70); Rheumatoid Factor

If the ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039).

Preferred Specimen(s)

4 mL serum

Minimum Volume

2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric


Immunoassay (IA) • Immunoturbidimetric Assay

Performing Laboratory

Quest Diagnostics - California Region

Reference Range(s)

See individual tests

Alternative Name(s)

Systemic Lupus Erythematosus (SLE), Thyroiditis, FANA, Fluorescent ANA, Progressive ANA, Hep-2, Antinuclear Antibody Screen

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
45061060RIBOSOMAL P ANTIBODY13636-6Ribosomal P Ab
45060420ANA SCREEN, IFA42254-3Nuclear Ab
45061010DNA (DS) ANTIBODY5130-0DNA double strand Ab
45009300COMPLEMENT COMPONENT C3C4485-9Complement C3
45009600COMPLEMENT COMPONENT C4C4498-2Complement C4
45003900RHEUMATOID FACTOR11572-5Rheumatoid factor
45061040SCL-70 ANTIBODY26975-3SCL-70 extractable nuclear Ab
45029100THYROID PEROXIDASE ANTIBODIES8099-4Thyroperoxidase Ab
45061025SM ANTIBODY43182-5Smith extractable nuclear Ab
45061030SM/RNP ANTIBODY14030-1Smith extractable nuclear Ab+Ribonucleoprotein extractable nuclear Ab
45061015SJOGREN'S ANTIBODY (SS-A)33569-5Sjogrens syndrome-A extractable nuclear Ab
45061020SJOGREN'S ANTIBODY (SS-B)45142-7Sjogrens syndrome-B extractable nuclear Ab

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.