Test Center

My Recent Searches

  • No Recent Search.

My Tests Viewed

  • No Test Viewed.
  • Ordering Info

To view specimen requirements and codes please select your laboratory:

Not sure which laboratory serves your office? Call us 1-866-MYQUEST (1-866-697-8378)

HLA-DR4, Flow Cytometry

Test Code


CPT Code(s)


Preferred Specimen(s)

7 mL whole blood collected in an ACD solution B (yellow-top) tube or 5 mL whole blood collected in a sodium heparin (green-top) tube

Minimum Volume

3 mL ACD solution (yellow-top) or 1 mL sodium heparin (green-top)

Alternative Specimen(s)

5 mL whole blood collected in an EDTA (lavender-top)

Transport Container

See Preferred Specimen(s)

Transport Temperature

Room temperature

Reject Criteria

Received refrigerated • Received frozen


Flow Cytometry (FC)

This test was developed and its performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.

Reference Range(s)

A positive result indicates the presence of HLA-DR4 antigen which is associated with an increased risk of an adverse reaction to vaccination with Lyme disease vaccine.

Clinical Significance

Testing for the presence of HLA-DR4 antigen in a patient is used to determine the potential risk of developing of lyme arthritis from infection with Borrelia burgdorferi or vaccination with lyme vaccine.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
1359HLA DR44983-3HLA-DR4

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.