Lactoferrin, Stool

CPT Code(s)

83630

Preferred Specimen(s)

1 g Stool collected in a plastic screw-cap container

Minimum Volume

0.3 g

Collection Instructions

Collect undiluted feces in clean, dry, sterile leak proof container.Do not add fixative or preservative. From collection time to the time stool is frozen must not exceed 48 hours. Patients may collect stool and hold at room temperature until it can be properly frozen. The time held at room temperature must not exceed 48 hours from time of collection. Specimens can be delivered to PSC or physicians office for freezing and delivery to the laboratory.

Transport Temperature

Frozen

Specimen Stability

Room temperature: See Instructions

Refrigerated: 48 hours

Frozen: 21 days

Reject Criteria

Thawed Stool • Specimen collected in formalin • MF • SAF • or
PVA • Cary-Blair media

Methodology

Immunoassay

Performing Laboratory

Quest Diagnostics Nichols Institute

33608 Ortega Highway

San Juan Capistrano, CA 92690-6130

Setup Schedule

Set up: 2 days a week a.m.; Report available: 1 day

Limitations

False-positive results are observed in breast-fed infants.

Reference Range(s)

NEGATIVE

Clinical Significance

The Lactoferrin IBD-CHEK^® is a qualitative (QL) Enzyme Linked Immunosorbent Assay (ELISA) for measuring concentrations of fecal lactoferrin, a marker for leukocytes. A positive level is an indicator of intestinal inflammation. The test can be used as an in vitro diagnostic aid to distinguish patients with active inflammatory bowel disease (IBD) from those with non inflammatory irritable bowel syndrome (IBS).