Cystic Fibrosis Carrier Screening

What Causes Cystic Fibrosis?

Cystic fibrosis is a genetic disorder. A child must inherit two defective CF genes (one defective gene from each parent) to have the disease.

A person who has inherited only one defective CF gene is a carrier of cystic fibrosis and does not have the disease but can pass it on to his or her children. This person can also pass on carrier status.

  • If only one parent is a carrier of a defective CF gene, the child will not have CF. But there is a 50% (1-in-2) chance that the child will be a CF carrier.
  • If both parents are carriers, there is a 25% (1-in-4) chance that the child will have CF, but a 50% chance that the child will be a carrier.

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Author: Debby Golonka, MPHLast Updated: June 26, 2007
Medical Review: Michael J. Sexton, MD - Pediatrics
Susanna McColley, MD - Pediatric Pulmonology

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Topic Contents
 What Is Cystic Fibrosis?
Arrow PointerWhat Causes Cystic Fibrosis?
 What Is Carrier Screening?
 Who Should Be Screened?
 What If I Am a Carrier?
 Is Screening Accurate?
 Should I Be Screened?
 Why Not Be Screened?
 Other Places To Get Help
 Related Information
 References
 Credits