Catecholamines in Urine

Dopamine Measurement in Urine, Epinephrine Measurement in Urine, Metanephrine Measurement in Urine, Norepinephrine Measurement in Urine, Vanillymandelic Acid Measurement in Urine

Test Overview

A test for catecholamines measures the amount of the hormones epinephrine, norepinephrine, metanephrine, and dopamine in the blood. These catecholamines are made by nerve tissue, the brain, and the adrenal glands. Catecholamines help the body respond to stress or fright and prepare the body for "fight-or-flight" reactions.

The adrenal glands make large amounts of catecholamines as a reaction to stress. The main catecholamines are epinephrine (adrenaline), norepinephrine (noradrenaline), and dopamine. They break down into vanillylmandelic acid (VMA) and metanephrine, which are passed in the urine.

Catecholamines increase heart rate, blood pressure, breathing rate, muscle strength, and mental alertness. They also lower the amount of blood going to the skin and increase blood going to the major organs, such as the brain, heart, and kidneys.

Certain rare tumors (such as a pheochromocytoma) can increase the amount of catecholamines in the blood. This causes high blood pressure, excessive sweating, headaches, fast heartbeats (palpitations), and tremors.

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Author:	Jan Nissl, RN, BS	Last Updated: August 21, 2006
Medical Review:	Caroline S. Rhoads, MD - Internal Medicine Alan C. Dalkin, MD - Endocrinology
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