Syphilis Tests

Microhemagglutination assay (MHA-TP), (Syphilis Test), Rapid Plasma Reagin (RPR) Test, (Syphilis Test), Venereal Disease Research Laboratory (VDRL) Test, (Syphilis Test)

Why It Is Done

A test for syphilis is done to:

  • Screen for syphilis or monitor treatment for a syphilis infection. Screening tests help your doctor look for a certain disease or condition before any symptoms appear. This increases the chance of finding the infection when it can be cured or treated to avoid long-term problems.
    • Some states require the VDRL screening test before a couple can obtain a marriage license.
    • The Centers for Disease Control and Prevention (CDC) and the U.S. Preventive Services Task Force (USPSTF) recommend that all pregnant women be screened for syphilis early in pregnancy.
  • Confirm that a syphilis infection is present.

A syphilis infection can spread through the bloodstream to all parts of the body. If not treated, syphilis can cause severe heart disease, brain damage, spinal cord damage, blindness, and death.


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Author: Kathe Gallagher, MSWLast Updated: October 2, 2007
Medical Review: Kathleen Romito, MD - Family Medicine
Jeanne Marrazzo, MD, MPH - Infectious Disease

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Topic Contents
 Test Overview
Arrow PointerWhy It Is Done
 How To Prepare
 How It Is Done
 How It Feels
 Risks
 Results
 What Affects the Test
 What To Think About
 References
 Credits