Colposcopy and Cervical Biopsy

Cervical Biopsy and Colposcopy, Cervical Exam

Test Overview

Colposcopy is a way for your doctor to use a special magnifying device to look at your vulva, vagina, and cervix. If a problem is seen during colposcopy, a small sample of tissue (biopsy) may be taken from the cervix or from inside the opening of the cervix (endocervical canal). The sample is looked at under a microscope.

See an illustration of the vagina or cervix .

Colposcopy is usually done to look at the vagina and cervix when a Pap test is abnormal. Many abnormal Pap tests are caused by viral infections, such as human papillomavirus (HPV) infection, or other types of infection, such as those caused by bacteria, fungi (yeast), or protozoa (Trichomonas). Natural cervical cell changes (atrophic vaginitis) related to menopause can also cause an abnormal Pap test. In some cases, untreated cervical cell changes that cause abnormal Pap tests may progress to precancerous or cancerous changes.

During colposcopy, your doctor uses a lighted magnifying device that looks like a pair of binoculars (colposcope). The colposcope allows your doctor to see problems that would be missed by the naked eye. A camera can be attached to the colposcope to take pictures or videos of the vagina and cervix.

Your doctor may put vinegar (acetic acid) and sometimes iodine (Lugol's solution) on the vagina and cervix with a cotton swab or cotton balls to see problem areas more clearly.

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Author:	Shannon Erstad, MBA/MPH	Last Updated: March 16, 2006
Medical Review:	Adam Husney, MD - Family Medicine Deborah A. Penava, BA, MD, FRCSC, MPH - Obstetrics and Gynecology
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