Chlamydia Tests

How It Is Done

Direct sample

In a direct sample, a sample of body fluid is taken from the affected area. In adults, these areas may include the cervix, urethra, rectum, or eye.

  • For men. To collect a sample from the urethra or rectum, your health professional will insert a swab into the opening of your urethra or rectum to collect a sample. A sample from the urethra is more likely to detect chlamydia if a man has not urinated for at least 2 hours before the sample is taken.
  • For women. To collect a sample from the cervix, you will take off your clothes below the waist and drape a cloth around your waist. You will lie on your back on an examination table with your feet raised and supported by stirrups. This allows your health professional to examine your vagina and genital area. Your health professional will insert an instrument with curved sides (speculum) into your vagina. The speculum gently spreads apart the vaginal walls so the inside of the vagina and the cervix can be looked at. Samples are collected from the cervix with a swab or small brush.
  • To collect a sample from your eye, your health professional will gently brush the insides of your lower and upper eyelids with a swab.

In rare cases, a throat culture may be done.

Urine sample

If a urine sample is collected for nucleic acid amplification testing (such as PCR testing), do not urinate for 2 hours before the test. Do not wipe the genital area clean before urinating. Collect the first part of your urine stream, immediately as you begin urinating.


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Author: Jan Nissl, RN, BSLast Updated: February 5, 2007
Medical Review: Martin Gabica, MD - Family Medicine
Kathleen Romito, MD - Family Medicine
Jeanne Marrazzo, MD, MPH - Infectious Disease

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Topic Contents
 Test Overview
 Why It Is Done
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