Topic Overview
What is polycystic ovary syndrome (PCOS)?
Polycystic ovary syndrome (say “pah-lee-SIS-tik OH-vuh-ree
SIN-drohm”) is a problem in which a woman’s
hormones are out of balance. It can cause problems
with your periods and make it difficult to get pregnant. PCOS may also cause
unwanted changes in the way you look. If it is not treated, over time it can
lead to serious health problems, such as
diabetes and heart disease.
Polycystic ovary syndrome (or PCOS) is common, affecting as many
as 1 in 15 women. Often the symptoms begin in the teen years. Treatment can
help control the symptoms and prevent long-term problems.
What are hormones, and what happens in PCOS?
Hormones are chemical messengers that trigger many different
processes, including growth and energy production. Often, the job of one
hormone is to signal the release of another hormone.
For reasons that are not well understood, in PCOS the hormones
get out of balance. One hormone change triggers another, which changes another.
This makes a vicious circle of out-of-balance hormones. For example:
- The sex hormones get out of balance.
Normally, the
ovaries make a tiny amount of male sex hormones (androgens). In PCOS, they start making slightly more
androgens. This may cause you to stop
ovulating, get acne, and grow extra facial and body
hair.
- The body may have a problem using
insulin, called
insulin resistance. When the body doesn't use insulin
well, blood sugar levels go up. Over time, this increases your chance of
getting diabetes.
What are the symptoms?
Symptoms tend to be mild at first. You may have only a few
symptoms or a lot of them. The most common symptoms are:
- Acne.
- Weight gain and trouble
losing weight.
- Extra hair on the face and body. Often women get
thicker and darker facial hair and more hair on the chest, belly, and
back.
- Thinning hair on the scalp.
- Irregular periods.
Often women with PCOS have fewer than nine periods a year. Some women have no
periods. Others have very heavy bleeding.
- Fertility problems. Many
women with PCOS have trouble getting pregnant (infertility).
- Depression.
Most women with PCOS grow many small
cysts on their ovaries. That is why it is called
polycystic ovary syndrome. The cysts are not harmful, but lead to hormone
imbalances.
What causes PCOS?
The symptoms of PCOS are caused by changes in hormone levels.
There may be one or more causes for the hormone level changes.
PCOS seems to run in families, so your chance of having it is
higher if other women in your family have PCOS, irregular periods, or diabetes.
PCOS can be passed down from either your mother's or father's side.
How is PCOS diagnosed?
To diagnose PCOS, the doctor will:
- Ask questions about your past health,
symptoms, and
menstrual cycles.
- Do a physical exam to
look for signs of PCOS, such as extra body hair and
high blood pressure. The doctor will also check your
height and weight to see if you have a healthy
body mass index (BMI).
- Do a number of
lab tests to check your blood sugar, insulin, and other hormone levels. Hormone
tests can help rule out thyroid or other gland problems that could cause
similar symptoms.
You may also have a pelvic
ultrasound to look for cysts on your ovaries. Your
doctor may be able to tell you that you have PCOS without an ultrasound, but
this test will help him or her rule out other problems.
How is it treated?
Regular exercise, healthy foods, and weight control are key
treatments for PCOS. Medicines to balance hormones may also be used. Getting
treatment can reduce unpleasant symptoms and help prevent
long-term health problems.
The first step in managing PCOS is to get regular exercise and
eat heart-healthy foods. This can help lower blood pressure and cholesterol and
reduce the risk of diabetes and heart disease. It can also help you lose weight
if you need to.
- Try to fit in
moderate activity and/or
vigorous activity on a regular basis. Walking is a
great exercise that most people can do.
- Eat heart-healthy diet.
In general, this diet has lots of vegetables, fruits, nuts, beans, and whole
grains. It also limits foods that are high in saturated fat, such as meats,
cheeses, and fried foods. If you have blood sugar problems, try to eat about
the same amount of
carbohydrate at each meal. A
registered dietitian can help you make a meal
plan.
- Most women with PCOS can benefit from losing weight. Even
losing 10 lb (4.5 kg) may help
get your hormones in balance and regulate your menstrual cycle. PCOS can make
it hard to lose weight, so work with your doctor to make a plan that can help
you succeed.
- If you smoke, consider quitting. Women who smoke
have higher androgen levels that may contribute to PCOS symptoms.1 Smoking also increases the risk for heart disease. For more
information, see the topic
Quitting Tobacco Use.
A doctor may also prescribe medicines, such as:
- Birth control pills. They can help your
periods be regular and can reduce symptoms such as excess facial hair and acne.
An androgen-lowering medicine, spironolactone, may be used with birth control
pills to help reduce symptoms even more. These medicines are not used if you
are trying to get pregnant.
- A diabetes medicine called metformin.
It can help control insulin and blood sugar levels and reduce androgen levels.
This lowers your risk for diabetes and heart disease and can help restore
regular menstrual cycles and fertility.
- Fertility medicines, if
you are trying to get pregnant.
It is important to see your doctor for follow-up to make sure
treatment is working and adjust it if needed. You may also need regular tests
to check for diabetes, high blood pressure, and other possible problems.
It may take a while for treatments to help with symptoms such as
facial hair or acne. In the meantime:
- Over-the-counter or prescription acne
medicines may help with skin problems.
- Waxing, tweezing, and
shaving are easy ways to get rid of unwanted hair. Electrolysis or laser
treatments can permanently remove the hair but are more expensive. Your doctor
can also prescribe a skin cream that slows hair growth for as long as you use
it regularly.
It can be hard to deal with having PCOS. If you are feeling sad
or depressed, it may help to talk to a counselor or to other women who have
PCOS. Ask your doctor about local support groups, or look for an online group.
It can make a big difference to know that you are not alone. For more
information, see the topic
Depression or
Depression in Children and Teens.
Frequently Asked Questions
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