Opioids for restless legs syndrome

Examples

Generic NameBrand Name
codeinePhenaphen with codeine, Tylenol with codeine
hydrocodoneAnexsia, Lorcet, Tylox, Vicodin
oxycodonePercodan
propoxypheneDarvon
tramadolUltram

How It Works

Opioids are narcotics and are usually used to relieve pain. It is not known how these medications relieve symptoms of restless legs syndrome.

Why It Is Used

Opioids are usually used for restless legs syndrome only when other drugs have not relieved symptoms. A doctor will usually prescribe only a small amount initially to see whether it helps.

How Well It Works

Low doses of opioids are sometimes used on an as-needed basis to treat symptoms that appear irregularly.

Side Effects

Dizziness, sedation, nausea, vomiting, and constipation are the major side effects of opioids. Addiction or a tolerance can develop.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

More study is needed to discover the full range of side effects. Opioids have not yet been reviewed by the U.S. Food and Drug Administration specifically for treatment of restless legs syndrome.

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Author: Kathe Gallagher, MSW
Cynthia Tank
Last Updated: April 4, 2007
Medical Review: Adam Husney, MD - Family Medicine
Wayne A. Hening, MD - Neurology
Karin M. Lindholm, DO - Neurology

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Topic Contents
 Examples
 How It Works
 Why It Is Used
 How Well It Works
 Side Effects
 What To Think About