Mucolytics for cystic fibrosis

Examples

Generic Name	Brand Name
acetylcysteine	Mucomyst

How It Works

Mucolytics dissolve mucus in the lungs or intestines, making the mucus thinner and less sticky. However, these drugs are not used very much because they can irritate the lungs.

Why It Is Used

Mucolytics are occasionally prescribed for respiratory problems, such as cystic fibrosis.

How Well It Works

Mucolytics work well for only a few people. Some people have allergic reactions from using acetylcysteine (Mucomyst), and a bronchospasm may occur.

Side Effects

Call your doctor if:

• Your chest feels tight or you are wheezing or spitting up blood.
• You are having trouble breathing.
• You have a skin rash or other irritation.

The following side effects may go away after you adjust to the medicine. If they do not go away or if they are bothering you, call your doctor.

• Nausea
• Vomiting
• Fever
• Runny nose
• Drowsiness
• Clammy skin

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Using mucolytics may actually cause more mucus to form.

Acetylcysteine irritates the lungs and causes more coughing. In addition, it has a bad smell and taste and it is expensive.

Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.

Author:	Debby Golonka, MPH	Last Updated: June 26, 2007
Medical Review:	Michael J. Sexton, MD - Pediatrics Susanna McColley, MD - Pediatric Pulmonology
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