Expectorants for chronic obstructive pulmonary disease (COPD)

Examples

Prescription expectorants

Generic Name	Brand Name
guaifenesin	Fenesin, Humibid L.A., Organidin NR, Sinumist-SR Capsulets
iodinated glycerol	Iophen, Organidin, Par Glycerol, R-Gen

Nonprescription expectorants

Generic Name	Brand Name
guaifenesin	Breonesin, Guiatuss, Halotussin

Guaifenesin is available in tablet, capsule, or liquid form. Iodinated glycerol is available in liquid form. Your health professional will help you decide which form is best for you.

How It Works

Expectorants may keep mucus from sticking to the airways of the lungs, making it easier to cough up. They are no longer commonly used.

Why It Is Used

Expectorants may be used in chronic obstructive pulmonary disease (COPD) when it is difficult to cough up mucus from the lungs. However, expectorants are not commonly recommended for COPD treatment.¹

How Well It Works

Expectorants may bring some relief from symptoms, but there is no evidence that they improve lung function.²

Side Effects

Some people who use guaifenesin experience nausea, vomiting, dizziness, rash, and itching.

Some people who use iodinated glycerol develop a rash. In rare cases, people who use this medication for long periods of time may develop an underactive thyroid gland (hypothyroidism).

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

The best way to reduce development of mucus is to stop smoking.

Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.

Author:	Lila Havens Robin Parks, MS	Last Updated: June 16, 2006
Medical Review:	Renée M. Crichlow, MD - Family Medicine Kathleen Romito, MD - Family Medicine Ken Y. Yoneda, MD - Pulmonology
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