Other treatment for warts
Immunotherapy and bleomycin are only used if all other
treatment fails. Immunotherapy triggers your immune system to destroy the virus
causing the wart. Because some of the substances used for immunotherapy are
expensive, dangerous, or require specialized handling, such treatment is
considered only after other methods have failed.
Immunotherapy
options include contact sensitizers, imiquimod, and interferon.
The following table compares these treatments for warts.
Treatments for warts
| Type of
treatment |
Advantages |
Disadvantages |
|
Contact sensitizers (immunotherapy)
|
- Contact sensitizers attack the virus that
causes the wart.
- One review of studies reports that the sensitizer
DNCB removed warts in 80% of the people using it, compared to 38% in people
using a
placebo.1
|
- Contact sensitizers have potential for
causing severe
allergic reaction.
- They are not widely
used because of cost and risks to doctors.
- They are not recommended
for pregnant women.
|
|
Imiquimod (immunotherapy)
|
- Imiquimod is applied at
home.
- It is considered effective treatment for genital warts and is
being used more in other types of warts.
- It attacks the virus that
causes the wart.
|
- There is little information on its
effectiveness for nongenital warts.
- It can cause relatively mild
skin irritation, burning, and blistering.
- It is expensive.
|
|
Interferon injection
(immunotherapy)
|
- Interferon attacks the virus that causes
the wart.
|
- Interferon is usually injected into the
wart.
- It is considered experimental and is not widely
available.
|
|
Bleomycin injection
|
- Bleomycin is injected into warts that have
been resistant to other treatments.
|
- There is no consistent evidence of
bleomycin's effectiveness.2
- It causes pain
during and after injection into a wart, and is usually used as a last
resort.
- It can cause scarring, nail damage, and skin color
changes.
- It is expensive.
- It is toxic and not
recommended for children and pregnant women.
|
|
| Author: |
Caroline Rea, RN, BS, MS |
Last Updated: September 11, 2008 |
| Medical Review: |
Kathleen Romito, MD - Family Medicine
Alexander H. Murray, MD, FRCPC - Dermatology
|
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