If you have surgery for heart valve repair or replacement,
you will probably receive two types of medicine: anticoagulants (blood
thinners) and antibiotics.
Anticoagulants
You may need to take
anticoagulants for at least 3 months following heart
valve surgery. During this time, you are at the greatest risk of blood clot
formation around your repaired or replaced valve. These blood clots can break
off and travel to your brain, causing a
stroke, or to other organs, including kidneys,
intestines, and legs. Taking blood thinners can prevent these clots from
forming.
If your valve has been replaced with a mechanical valve,
you will need to take anticoagulants indefinitely, since the artificial valve
may stimulate clot formation. Some doctors also recommend taking low doses of
aspirin with anticoagulants. This is primarily because aspirin has been shown
to help reduce the risk of cardiovascular disease. But other doctors do not
feel taking aspirin lowers your risk of cardiovascular disease enough to
justify taking another medicine. Aspirin's anticlotting effect also can further
increase your risk for excessive bleeding, which is already a problem due to
the anticoagulants.
If your valve has been replaced with a
biological valve, or if you had valve repair, you may not need to take
anticoagulants for as long a time. In either case, anticoagulant therapy should
be continued for 3 months following surgery. The chances of clots forming
around a natural, reconstructed valve are significantly less than those of
valve replacement surgery, and two-thirds of those with biological valves are
able to stop taking an anticoagulant or aspirin after 3 months. But if you have
a history of irregular heartbeat (atrial
fibrillation) or presurgery problems with clots forming, or a dilated
left atrium, you will likely need to take anticoagulants indefinitely because
your risk of developing clots and having a stroke remains high.
Heart procedures such as valve surgery can also cause atrial fibrillation.
Atrial fibrillation in turn can also cause clots to form, and blood-thinning
medicine can help prevent these clots also.
There are risks
associated with anticoagulants. You may bleed more heavily from minor injury,
or even bleed spontaneously. You may need to have your medicine and blood
checked regularly, and you must consult your doctor before starting or changing
any of your medicines while you are on anticoagulants.
Pregnant
women are generally advised not to take the blood thinner warfarin (such as
Coumadin), because it is known to cause birth defects. If you become pregnant
while taking warfarin, your doctor may recommend that you switch to a
low-molecular-weight form of heparin (another anticoagulant) during the first
and third
trimesters of your pregnancy, and take warfarin only
during the second trimester. Long-term use of these heparin formulations is not
recommended, because it is associated with
osteoporosis and
thrombocytopenia.
Vitamin K can decrease
the effectiveness of anticoagulants. But you should not try to eliminate
vitamin K from your diet. Rather, try to make sure that your vitamin K intake
remains relatively constant from day to day.
Antibiotics
If you have an
artificial valve, you may need to take
antibiotics before you have certain
dental or surgical procedures. The antibiotics help
prevent an infection in your heart called
endocarditis.