Dupuytren's disease most commonly affects people of
northern European heritage. It is rare in people of African or Asian descent.
Heredity is thought to be a factor, since Dupuytren's disease tends to occur
most often among close family members.
The risk of Dupuytren's disease increases with age: it occurs most
often in people age 50 and older.1 Men are 7 to 15
times more likely than are women to have severe Dupuytren's disease that
requires surgical treatment. Older women often develop a milder form of the
disease.2 Dupuytren's disease is very rare in
children.
Up to 30% of men older than 65 with a Northern European genetic
background will have Dupuytren's disease.3