Other conditions with symptoms similar to Reye's syndrome

Reye's syndrome is very rare, and many disorders have similar symptoms. Other diseases and conditions that will be considered as a cause of symptoms before a diagnosis of Reye's syndrome is made include:

  • Metabolism problems. Most of these disorders are related to liver enzyme defects or protein and fatty metabolism problems and are usually diagnosed before a child is 3 years of age. Symptoms often include frequent low blood sugar levels (hypoglycemia), an enlarged heart, and muscle weakness. Another child in the family usually has the disorder as well.
  • Effects of drugs (drug intoxication), such as aspirin.
  • Poisoning, including from illegal drugs.
  • Head injury that a parent or adult may not have seen or known about.
  • Infection of the brain and spinal cord.
  • Kidney failure.


Author: Sabra L. Katz-Wise
Ralph Poore
Last Updated: October 12, 2006
Medical Review: Michael J. Sexton, MD - Pediatrics
Thomas Emmett Francoeur, MDCM, CSPQ, FRCPC - Pediatrics

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