Older adults often have isolated
systolic high blood pressure and normal
diastolic blood pressure (isolated systolic
hypertension, or ISH). In isolated systolic hypertension, systolic blood
pressure is elevated (above 140 mm Hg), but diastolic blood pressure stays
lower than 90 mm Hg. This type of
high blood pressure is more common in older adults,
especially older women. In fact, the majority of people older than 60 who have
high blood pressure have isolated systolic high blood pressure.1
ISH should be treated because it can cause damage to organs such as
the brain, kidneys, heart, or eyes. A major study (SHEP) determined that
treatment resulted in a 27% decrease in heart disease, a 36% decrease in
stroke, and decreased the development of heart failure.1 However, older people are more prone to the low blood
pressure (hypotensive) side effects—such as lightheadedness or slow
heartbeat—of some medicines used to treat high blood pressure. Therefore,
isolated systolic high blood pressure should be treated without excessively
lowering diastolic blood pressure.2
How much to lower blood pressure is an issue for older people who
also have
heart disease. A sudden, large drop in blood pressure
may reduce blood flow to the heart and brain. Therefore, reducing blood
pressure gradually and modifying treatment if symptoms occur is often the best
approach, especially in people with valvular heart disease.
A diastolic blood pressure of 85 to 89 mm Hg may be high enough to
avoid side effects such as lightheadedness and low enough to protect against
many of the complications of high blood pressure, but it's not optimal, even in
older adults. Systolic pressure usually can be reduced by 10% without many of
the other problems caused by reduced blood flow to the heart.
Treatment of ISH often begins with the use of a
diuretic, which seems to be effective in older people.
Other medicines that may be used include long-acting
calcium channel blockers,
beta-blockers, or angiotensin-converting enzyme (ACE)
inhibitors. Some experts recommend that older adults not take a beta-blocker
medicine. Beta-blockers generally are not needed in older adults who don't have
any complications associated with high blood pressure, such as heart
disease.