Syphilis is one of the most common
reportable infectious diseases in the United
States.1 It tends to be most common in large
metropolitan cities.
Since the discovery of the antibiotic penicillin, the incidence of
syphilis in the general population has dropped, as have many other infectious
diseases. But after hitting an all-time low in 2000, the rate of syphilis
infection has been going up.2
- Syphilis is most common in sexually active people 15 to 30 years of
age. This age range is considered a more sexually active period for most
people.3
- About 6 out of 10 syphilis
infections affect men who have sex with men.2
- The syphilis rate seems to be increasing among
men and women who have heterosexual sex.2
- There has been a rise in the number of people who
have both syphilis and the human immunodeficiency virus (HIV). This is especially the case among men who have
sex with men.2
Open syphilis sores provide easy access to transmit or receive HIV
infection during sexual intercourse. This may be particularly important in
those parts of the country, such as the southern half of the United States,
where rates of both infections are high.
Syphilis without another sexually transmitted disease is now more
commonly seen in adults older than 30 years of age.