Medicines that can cause constipation

Many prescription and nonprescription medicines can cause constipation. Examples include:

  • Antacids with aluminum.
  • Anticonvulsants.
  • Antidepressants.
  • Blood pressure medicines, especially clonidine or calcium channel blockers (for example, verapamil).
  • Calcium supplements.
  • Chemotherapy medicines.
  • Cold medicines (antihistamines).
  • Corticosteroids, such as prednisone.
  • Diuretics, such as Lasix and hydrochlorothiazide.
  • Iron supplements.
  • Levodopa.
  • Lipid-lowering agents, such as cholestyramine.
  • Medicines for Parkinson's disease.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs).
  • Opiates, including pain medicines with codeine.
  • Psychotropics.
  • Radiation therapy.

If you think that your constipation is caused by a medicine:

  • For prescription medicines, call the health professional who prescribed it to see whether you should stop taking the medicine or take a different one. An appointment may not be needed.
  • For nonprescription medicines, stop taking the medicine. Call your health professional if you feel you need to still take the medicine.


Author: Jan Nissl, RN, BSLast Updated: December 14, 2006
Medical Review: William M. Green, MD - Emergency Medicine
Jerome B. Simon, MD, FRCPC, FACP - Gastroenterology

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