When a Patient Tests Positive
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Treating chlamydia and gonorrhea

Chlamydia and gonorrhea infections are easily treated and cured with antibiotics. Below are the recommended treatments for standard infections, as outlined by the Centers for Disease Control and Prevention (CDC).[1,2]



Vertical dotted lineRecommended regimens for treatment

Azithromycin 1 g orally in a single dose


Doxycycline 100 mg orally twice a day
for 7 days

For more information on treating chlamydia in special populations, go to cdc.gov/std/treatment/2010/

Recommended regimens for treatment

Ceftriaxone 250 mg in a single intramuscular dose
PLUS Azithromycin 1 g orally in a single dose


Doxycycline 100 mg orally twice a day for 7 days*

For more information on treating gonorrhea in 
special populations, go to cdc.gov/std/

* Because of the high prevalence of tetracycline resistance 
   among Gonococcal Isolate Surveillance Project isolates,
   particularly those with elevated minimum inhibitory
   concentrations to cefixime, the use of azithromycin as
   the second antimicrobial is preferred.


Green rule page dividerContinuing to protect your patients

Unfortunately, chlamydia and gonorrhea reinfection is common among patients. And because the risk of pelvic inflammatory disease (PID) and ectopic pregnancy is higher with each repeat infection, it’s crucial to follow these recommendations from leading health organizations[3-5]

  • Retesting patients after 3 months once they are treated for chlamydia and gonorrhea[3,4]
  • Advising patients to abstain from sex until after they and their sexual partner(s) have been treated[2-4]
  • Educating and counseling patients on ways they can avoid contracting sexually transmitted infections (STIs) by using recommended prevention methods, including[2,6]
    - Abstinence
    - Condom use
    - Limiting the number of sexual partners
  • Continuing to routinely screen patients to ensure possible future infections don’t
    go undiagnosed[6]

Green rule page dividerExpedited partner therapy

Expedited Partner Therapy (EPT) is another way to help protect your patients who have tested positive for chlamydia and gonorrhea. With EPT, healthcare providers can provide medication for the sexual partners of patients who have been diagnosed with chlamydia or gonorrhea without first examining them.[2,7,8]

EPT has been endorsed by leading health organizations such as the Centers for Disease Control and Prevention (CDC), the American Medical Association (AMA), and the American College of Obstetricians and Gynecologists (ACOG). The legal status of EPT varies from state to state, and you can find more information on individual state policies here.[2,7-9]



1. Centers for Disease Control and Prevention. CDC fact sheet: incidence, prevalence, and cost of sexually transmitted infections in the United States. http://www.cdc.gov/std/stats/sti-estimates-fact-sheet-feb-2013.pdf. Accessed February 23, 2015.

2. US Preventive Services Task Force. Final recommendation statement: chlamydia and gonorrhea: screening. http://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/chlamydia-and-gonorrhea-screening. Accessed February 25, 2015.

3. Centers for Disease Control and Prevention. Chlamydial infections–2010 STD treatment guidelines. http://www.cdc.gov/std/treatment/2010/chlamydial-infections.htm. Accessed February 27, 2015.

4. Centers for Disease Control and Prevention. Gonococcal infections–2010 STD treatment guidelines. http://www.cdc.gov/std/treatment/2010/gonococcal-infections.htm. Accessed February 27, 2015.

5. Nakatsukasa-Ono W, Howard H for the National Chlamydia Coalition. Practical strategies for improving chlamydia and gonorrhea retesting. http://ncc.prevent.org/products/committee-products/file/EC_October-2012-2.pdf. Accessed February 27, 2015.

6. Centers for Disease Control and Prevention. Sexually transmitted diseases (STDs). Expedited Partner Therapy. http://www.cdc.gov/std/ept. Accessed February 27, 2015.

7. The American Congress of Obstetricians and Gynecologists. Expedited partner therapy in the management of gonorrhea and chlamydia by obstetrician-gynecologists. http://www.acog.org/Resources-And-Publications/Committee-Opinions/Committee-on-Adolescent-Health-Care/Expedited-Partner-Therapy-in-the-Management-of-Gonorrhea-and-Chlamydia-by-Obstetrician-Gynecologists. Accessed February 27, 2015.

8. Centers for Disease Control and Prevention. Clinical prevention guidance. 2010 STD treatment guidelines. http://www.cdc.gov/std/treatment/2010/clinical.htm#a2. Accessed February 27, 2015.

9. American Medical Association Council on Ethical and Judicial Affairs. Report 6-A-08, Expedited partner therapy. https://download.ama-assn.org/resources/doc/code-medical-ethics/x-pub/807a.pdf. Accessed February 27, 2015.