As the leading cause of death in the US,1 heart disease is all too common. But guidelines are moving toward new kinds of cardiovascular testing that have the potential to save millions of more lives. Use the links below to jump to a specific section, or simply scroll down to read all about uncovering the hidden risks for heart disease and stroke.

Heart disease statistics
Cardiovascular guidelines
Identifying residual risk
     Inflammation risk factors
     Lipoprotein risk factors

Heart disease continues to be the leading cause of death in the US1

CVD causes 1 in every 3 deaths in the US

  • One American dies of CVD approximately every 40 seconds
  • 635,000 Americans per year will have a heart attack for the first time
  • Nearly half of all heart attack patients are found to have no prior risk that would indicate they are heading toward an attack
  • Many of the risk factors contributing to CVD are modifiable—such as cigarette smoking, high BMI, and high sodium intake

BMI=body mass index.


Disease State timeline
ATP=Adult Treatment Panel; ACC=American College of Cardiology; AHA=American Heart Association; CHD=coronary heart disease; LDL=low-density lipoproteins; HDL=high-density lipoproteins. 

Residual cardiovascular risk is still significant despite managing traditional risk factors

Older couple sitting on dockLDL levels are often not predictive of cardiovascular events such as heart attack or stroke, in both primary and secondary prevention settings. The AHA Get-With-The-Guidelines® initiative analysis revealed that a substantial proportion of CHD event patients were well within guideline-recommended targets for lipid panel values.

CHD pie chart

Identifying residual risk with emerging biomarkers

Contribution of these biomarkers is well proven and accepted by many guidelines and societies

Disease State Inflammation Chart
Disease State Lipoprotein Chart

Reference: 1. Go A et al; on behalf of the American Heart Association Statistics Committee and Stroke Statistics. Heart Disease and Stroke Statistics—2013 Update. Circulation. 2013;127:(e6-e245).