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Oral fluid drug testing1

The use of oral fluid (saliva) as a biological specimen for the detection of drugs of abuse is growing in popularity within the workplace. The increased popularity of oral fluid drug testing is due to inherent advantages over the standard urine drug test. Oral fluid specimen collection using Intercept is simple and non-invasive. Collection can occur at any time or location without embarrassment to the donor.

The specimen can be collected from the donor under direct observation, thus minimizing the potential for specimen tampering and/or adulteration. Oral fluid drug concentrations can be related to plasma free-drug concentrations and the pharmacological effects of drugs. As a result, oral fluid drug concentrations can provide information similar to that provided by plasma or blood drug concentrations.

Consideration should be given to the effect that some drugs or medical conditions have on the donor's ability to secrete oral fluid. As a result, oral fluid may not be available from all individuals at all times.2

Intercept tests for the following drug classes:

Amphetamines (including Ecstasy)

Cocaine

Marijuana

Opiates

Phencyclidine (PCP)


Orals fluid specimen six-panel test:

    Analyte

    Screen Cutoff

    Confirmation
    Cutoff

    Amphetamines

    100 ng/mL

    40 ng/mL

    Methamphetamines

    40 ng/mL

    40 ng/mL

    Opiates

    10 ng/mL

    10 ng/mL

    Benzoylecgonine

    5 ng/mL

    2 ng/mL

    Phencyclidine

    1 ng/mL

    0.5 ng/mL

    Marijuana metabolite

    1 ng/mL

    0.5 ng/mL

The table below shows the detection window for drugs of abuse using oral fluid.
    Drug   Detection Window
  for Oral Fluid

    Amphetamines

   24-36 hours

   Cocaine/Metabolite

   24-36 hours

   Opiates

   24-36 hours

   PCP

   24-36 hours

   THC/Metabolite

   Less than 24 hours


Specimen collection is easy:
Swab, Snap, Seal

View and print an Intercept oral fluid testing brochure.

View and print FAQs on Intercept oral fluid testing.

Take online oral fluid testing training.

For more information on oral fluid testing, contact an Employer Solutions sales representative.

1Use dependent on state law.
2 R. Haeckel and P. Hanecke, "Application of saliva for drug monitoring an in vivo model for transmembrane transport," Eur. J. Clin. Chem. Biochem., 1996, 34, 171-191.